Canino is located in the Maremma Laziale a short distance from the sea and near the Etruscan city of Vulci.
Vulci was one of the most important Etruscan settlements that between the seventh and fifth centuries BC enjoyed great economic prosperity and political prestige.
The city was conquered by the Romans who imposed their political strategy.
During the Saracen invasions the population took refuge in fortified towns nearby. The first document that mentions it is a bull by Pope Leo IV of the ninth century.
At the end of the fourteenth century, after having belonged to Viterbo and the family of the Prefects of Vico, it was assigned by the Holy See to Ranuccio III Farnese. It became part of the Duchy of Castro ordered by Pope Paul III Farnese for his son Pier Luigi, and this was a period of wealth and prosperity.
In 1649, after the destruction of Castro ordered by Pope Innocent X, it was forfeited to the Apostolic Camera.
At the beginning of the nineteenth century it became the residence of Luciano Bonaparte, Napoleon’s brother, named Prince of Canino by Pope Pius VII. His funeral monuments are located in the Bonaparte Chapel, inside the Church of the Holy Apostles John and Andrew.
In Canino Alessandro Farnese was born in 1468 who became Pope Paul III in 1534 and has led the family to its maximum splendour.