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San Quirico is a small village, and perhaps is the origin of the town of Serrone as here are the remains of its cyclopean walls. The walls bear witness to an origin previous to the foundation of Rome, perhaps attributed to the Ernici people.

In San Quirico is a particular church that dates back to 1600 and is dedicated to San Quirico, a saint very venerated, from which the area takes its name.

Its territory is very suitable for vines and San Quirico is recognized for the quality of its Cesanese grapes and wine